There are two semesters in Don Bosco Cristo Rey’s academic year. The final grade earned for a course is the average of semester 1 and 2. Semester grades are weighted using this formula: Q1 (40%) + Q2 (40%) + Semester Exam (20%). The following scale is used to determine letter grades and GPA:
| A+ | 97-100 | 4.3 |
| A | 93-96 | 4.0 |
| A- | 90-92 | 3.7 |
| B+ | 87-89 | 3.3 |
| B | 83-86 | 3.0 |
| B- | 80-82 | 2.7 |
| C+ | 77-79 | 2.3 |
| C | 73-76 | 2.0 |
| C- | 70-72 | 1.7 |
| D+ | 67-69 | 1.3 |
| D | 65-66 | 1.0 |
| F | 64 and below | 0.0 |
| I | Incomplete | No credit |
| Withdrawn | No credit |